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  • The synovial environment steers cartilage deterioration and regeneration

    Osteoarthritis (OA) was recently defined as an epidemic, and the lack of effective treatment is highly correlated to the limited knowledge regarding the underlying pathophysiology. Failure to regenerate upon trauma is thought to be one of the underlying causes for degenerative diseases, including OA. To investigate why lesions within an OA environment fail to heal, a heterogeneous cell population was isolated from the synovial fluid (SF) of OA patients.

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  • Chondromalica: Causes, Risk Factors, and Prevention

    Chondromalacia patella, also known as runner's knee, is a knee condition that can cause pain and grinding when the knee is flexed. It's due to the breakdown in the cartilage on the undersurface of the kneecap (patella) that causes bones to rub against each other. Overuse (especially from running or cycling), trauma, such as a fracture, or a misalignment of the kneecap and femur can all cause chondromalacia.

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  • 10 Best Joint Supplements for Knee Pain, Joint Support, & Cartilage

    Joint supplements are natural dietary supplements that help relieve joint pain, protect cartilage, support joint health, and restore range of motion. Whether you have cracking knees, joint pain, or arthritis, taking the best joint supplement can offer natural relief.

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  • Pain Relief After Total Knee Arthroplasty with Intravenous and Periarticular Corticosteroid

    Total knee arthroplasty (TKA) is a cost-effective procedure, but it is also associated with substantial postoperative pain. The present study aimed to compare pain relief and functional recovery after TKA among groups that received intravenous corticosteroids, periarticular corticosteroids, or a combination of both.

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  • What Is Bone Marrow Edema in the Knee?

    Bone marrow edema (BME) is when normal fatty bone marrow—the spongy tissue in the center of bones—is replaced with a watery mix of fluid and blood. Also known as a bone marrow lesion, BME occurs when arthritis, an injury, or a fracture damages the normal bone structure.

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